75168-11-5
中文名稱
10-壬基吖啶橙溴化物
英文名稱
NONYL ACRIDINE ORANGE
CAS
75168-11-5
分子式
C26H38BrN3
分子量
472.5
MOL 文件
75168-11-5.mol
更新日期
2024/12/23 17:39:06
75168-11-5 結(jié)構(gòu)式
基本信息
中文別名
10-壬基溴代吖啶橙吖啶橙 10-溴壬烷
10-壬基吖啶橙溴化物
3,6-雙(二甲基胺)-10-壬基溴代吖啶
線粒體膜電位熒光探針10-壬基吖啶橙溴化物
英文別名
NAOA-1372
NONYL ACRIDINE ORANGE
10-nonyl Acridine Orange
NONYL-ACRIDINE ORANGE (NAO)
10-NONYLACRIDINE ORANGE BROMIDE
ACRIDINE ORANGE 10-NONYL BROMIDE
Nonyl acridine orange *CAS 75168-11-5*
10-N-NONYL-3,6-BIS(DIMETHYLAMINO)ACRIDINIUM, BR
3,6-BIS(DIMETHYLAMINO)-10-NONYLACRIDINIUM BROMIDE
所屬類別
生物化工：熒光成像物理化學(xué)性質(zhì)
熔點(diǎn)≥250 °C(lit.)
儲(chǔ)存條件2-8°C
溶解度DMSO: soluble
形態(tài)粉末
顏色橙紅色
最大波長(λmax)495 nm
生物領(lǐng)域應(yīng)用Detecting cardiolipin,mitochondrial membrane potential,risk of type 2 diabetes,cardiotoxicity,prostate cancer; apoptosis assay; drug screening assay; hematotoxicity assay; treating arthritic disorders; in photodynamic ther
安全數(shù)據(jù)
常見問題列表
生物活性
Acridine Orange 10-Nonyl Bromide 是心磷脂的熒光探針 (λex: 489 nm, λem: 525 nm)。體內(nèi)研究
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipin (λ ex : 489 nm, λ em : 525 nm) which can be used to quantify the cardiolipin in isolated mitochondria. when Acridine Orange 10-Nonyl Bromide interacts with cardiolipin, the dye excitation and emission wave lengths shift from 496 and 525 nm to 450 and 640 nm, respectively. Increasing amounts of cardiolipin (0 to 30 μM) and other acidic phospholipids in thin-walled vesicles added to Acridine Orange 10-Nonyl Bromide (45 μM) changes the red fluorescence emission measured at 640 nm according to the liposome composition.