63686-79-3
中文名稱
1-[4-[2-(環(huán)丙基甲氧基)乙氧基]苯氧基]-3-[(異丙基)氨基]-2-丙醇鹽酸鹽
英文名稱
Cicloprololum [Latin]
CAS
63686-79-3
分子式
C18H30ClNO4
分子量
359.888
MOL 文件
63686-79-3.mol
63686-79-3 結(jié)構(gòu)式
基本信息
中文別名
鹽酸環(huán)丙洛爾1-[4-[2-(環(huán)丙基甲氧基)乙氧基]苯氧基]-3-[(異丙基)氨基]-2-丙醇鹽酸鹽
英文別名
Cicloprololum [Latin]Cicloprolol (hydrochloride)
1-[4-[2-(Cyclopropylmethoxy)ethoxy]phenoxy]-3-[(1-methylethyl)amino]-2-propanol hydrochloride
常見(jiàn)問(wèn)題列表
生物活性
Cicloprolol 是部分 β1-腎上腺素能受體 (β 1-adrenoceptor) 激動(dòng)劑。靶點(diǎn)
Adrenoceptor
體外研究
Cicloprolol is a partial β1-adrenoceptor agonist considered for the treatment of patients with coronary artery disease and impaired left ventricular function. The new β-adrenoceptor partial agonist Cicloprolol acts as a β-agonist at normal levels and as a β-antagonist at high levels of adrenergic discharge. Treatment with Cicloprolol should protect the heart against excessive stimulation, while providing a baseline level of sympathetic drive. Cicloprolol has a weak β1-agonistic effect at normal levels of adrenergic discharge and acts as an antagonist at high levels of discharge.