63631-36-7
63631-36-7 結(jié)構(gòu)式
基本信息
中文別名
化合物 T10390化合物ASPERPHENAMATE
英文別名
AuranamideASPERPHENAMATE
N-Benzoyl-L-phenylalanine (S)-2-benzoylamino-3-phenylpropyl ester
(2S)-2-(Benzoylamino)-3-phenylpropanoic acid (2S)-2-(benzoylamino)-3-phenylpropyl ester
物理化學(xué)性質(zhì)
儲存條件-20°C儲存
溶解度DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
形態(tài)固體
顏色White to off-white
常見問題列表
生物活性
Asperphenamate 是來自Aspergillus flatiipes 的真菌代謝物，具有抗腫瘤活性，其對 T47D、MDA-MB-231 和 HL-60 細(xì)胞的IC50 值分別為 92.3 μM、96.5 μM 和97.9 μM。體外研究
Asperphenamate can inhibit cancer cell proliferation by fully inducing autophagy. asperphenamate showed inhibition effects against cathepsin L. At the same time, it also displayed weak inhibitory ability against cathepsin S.