A 23887 (5S,4'R)-3-Chloro-10,11-dihydro-N,N-dimethylspiro[5H-dibenzo[a,d]cycloheptene-5,1'-[2]cyclohexen]-4'-amine [1S,4R]-3'-Chloro-10',11'-dihydro-N,N-dimethylspiro[2-cyclohexene-1,5'-[5H]dibenzo[a,d]cyclohepten]-4-amine
應(yīng)用領(lǐng)域
用途一
A23887 is a potentially neuroleptic tetracyclic spiro amine that has affinity for dopamine D-2 receptors. It is important for defining the pharmacophore for D-2 antagonist activity due to its limited conformational freedom.
