56-88-2
56-88-2 結(jié)構(gòu)式
基本信息
(R)-S-(2-氨基-2-羧乙基)-L-半胱氨酸
S-[(2R)-2-氨基-2-羧基乙基]-L-高半胱氨酸
L(+)CYSTATHIONINE
CYSTATHIONINE, L-
L-CYSTATHIONINE, >= 98% (TLC)
CYSTATHIONINE, L-(DS)(REQUEST QUOTE)
(2R,7S)-2,7-Diamino-4-thiaoctanedioic acid
S-[(R)-2-Amino-2-carboxyethyl]-L-homocysteine
[R]-S-[2-AMINO-2-CARBOXYETHYL]-L-HOMOCYSTEINE
S-[(2R)-2-AMino-2-carboxyethyl]-L-hoMocysteine
L-Cystathionine,(R)-S-(2-Amino-2-carboxyethyl)-L-homocysteine
物理化學(xué)性質(zhì)
常見問題列表
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Human Endogenous Metabolite
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Homocysteine obviously induces the apoptosis of HUVECs, and this effect is significantly attenuated by the pretreatment with L-cystathionine. Furthermore, L-cystathionine decreases the production of mitochondrial superoxide anion and the expression of Bax and restrained its translocation to mitochondria, increases mitochondrial membrane potential, inhibits mitochondrial permeability transition pore (MPTP) opening, suppresses the leakage of cytochrome c from mitochondria into the cytoplasm, and downregulated activities of caspase-9 and caspase-3.
L-Cystathionine is an important metabolic intermediate in the L-cysteine transsulfuration pathway from L-methionine via L-homocysteine in mammalian tissues.