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55-10-7

中文名稱 3-甲氧基-4-羥基扁桃酸
英文名稱 4-Hydroxy-3-methoxymandelic acid
CAS 55-10-7
分子式 C9H10O5
分子量 198.17
MOL 文件 55-10-7.mol
更新日期 2024/11/06 17:52:05
55-10-7 結構式 55-10-7 結構式

基本信息

中文別名
3-甲氧基-4-羥基扁桃酸
4-羥基-3-甲氧基扁桃酸
英文別名
3-METHOXY-4-HYDROXY MANDELIC ACID
(+/-)-4-HYDROXY-3-METHOXYMANDELIC ACID
4-HYDROXY-3-METHOXYMANDELIC ACID
ALPHA,4-DIHYDROXY-3-METHOXYBENZENEACETIC ACID
DL-3-METHOXY-4-HYDROXYMANDELIC ACID
DL-4-HYDROXY-3-METHOXYMANDELIC ACID
DL-VANILLOMANDELIC ACID
HYDROXY-3-METHOXYMANDELIC ACID, D,L-4-
VANILLOMANDELIC ACID
VANILLYLMANDELIC ACID
VANILMANDELIC ACID
VMA
alpha,4-dihydroxy-3-methoxy-benzeneaceticaci
α,4-Dihydroxy-3-methoxybenzeneacetic acid
VMA, 98% (VANILLOMANDELIC ACID)
VANILLYLMANDELIC ACID 99%
Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-
4-HYDROXY-3-METHOXYMANDELICACID,REAGENT
(2S)-2-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)acetic acid
HYDROXYMETHOXYMANDELICACID
所屬類別
化學試劑:脂肪酸

物理化學性質

熔點132-134 °C (dec.)(lit.)
沸點255.48°C (rough estimate)
密度1.2539 (rough estimate)
折射率1.4570 (estimate)
儲存條件2-8°C
溶解度H2O: ~50 mg/mL
酸度系數(shù)(pKa)3.42±0.10(Predicted)
形態(tài)powder
顏色white to off-white
水溶解性易溶
JECFA Number2020
Merck9933
BRN2213227
LogP-0.212 (est)

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H315-H319
危險品標志Xi
危險類別碼36/37/38
安全說明26-36-37/39
WGK Germany3
海關編碼29181998

常見問題列表

概述
3-甲氧基-4-羥基扁桃酸是制備新型廣譜抗菌藥物甲氧芐胺嘧啶和香草醛的重要中間體,3-乙氧基-4羥基扁桃酸是制備乙氧基香草醛的中間體。香蘭素或乙基香蘭素為廣譜香料,可用作定香劑、調味劑和變味劑。
用途
3-甲氧基-4-羥基扁桃酸是制備新型廣譜抗菌藥物甲氧芐胺嘧啶和香草醛的重要中間體。
生物活性
Vanillylmandelic acid (VMA)是合成人工香草調味料的中間物,是兒茶酚胺的終末期代謝物。
體外研究

Vanillylmandelic acid has antioxidant activity, the IC 50 value is determined as the amount of VMA required to reduce 50% of the starting concentration of free radical is 33*10 -6 M in the UV-Vis decolourisation DPPH assay.

體內研究

Vanillylmandelic acid (intra-arterial injection over 1 min; 1, 10 and 100 mg/kg; the 60 min-observation period) produces a significant difference between vanillylmandelic acid groups and controls. Vanillylmandelic acid decreases the heart rate by 17.5%, 17.9% and 18.9% after 1, 10 and 100 mg/kg, respectively. Mean blood pressure is decreased by 13.5% in control animals as compared to 37%, 23% and 26% after 1, 10 and 100 mg/kg, respectively, in wistar rats.

3-甲氧基-4-羥基扁桃酸價格(試劑級)
報價日期產品編號產品名稱CAS號包裝價格
2024/11/08A133494-羥基-3-甲氧基-DL-扁桃酸, 98%
4-Hydroxy-3-methoxy-DL-mandelic acid, 98%
55-10-71g459元
2024/11/08A133494-羥基-3-甲氧基-DL-扁桃酸, 98%
4-Hydroxy-3-methoxy-DL-mandelic acid, 98%
55-10-75g1460元
2024/11/08A133494-羥基-3-甲氧基-DL-扁桃酸, 98%
4-Hydroxy-3-methoxy-DL-mandelic acid, 98%
55-10-725g6899元
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