53609-64-6
53609-64-6 結(jié)構(gòu)式
物理化學性質(zhì)
沸點288.88°C (rough estimate)
密度1.2266 (rough estimate)
折射率1.4650 (estimate)
儲存條件2-8°C
形態(tài)viscous liquid
顏色yellow
常見問題列表
生物活性
N-Bis(2-hydroxypropyl)nitrosamine 是一種具有致癌作用的試劑。體外研究
N-Bis(2-hydroxypropyl)nitrosamine is an agent with carcinogenic activity.
體內(nèi)研究
N-Bis(2-hydroxypropyl)nitrosamine causes the tumors to develop in the lung, liver, and thyroid of rats at a dose of 100 ppm, in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at a dose of 500 ppm, and in the lung, liver thyroid, esophagus, kidney, and urinary bladder of rats at both doses. Bisphenol A (BPA) enhances the susceptibility to thyroid carcinoma stimulated by N-Bis(2-hydroxypropyl)nitrosamine (DHPN; 2800 mg/kg) in rats.