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469-21-6

中文名稱 多西拉敏
英文名稱 DOXYLAMINE
CAS 469-21-6
分子式 C17H22N2O
分子量 270.37
MOL 文件 469-21-6.mol
更新日期 2024/08/07 14:10:10
469-21-6 結(jié)構(gòu)式 469-21-6 結(jié)構(gòu)式

基本信息

中文別名
多西拉敏
多沙胺雜質(zhì)
英文別名
oxylamine
DOXYLAMINE
NCI C60684
DOXYLAMINE USP/EP/BP
Doxylamine Hydrogen inate
2-dimethylaminoethoxyphenylmethyl-2-picoline
alpha-Dimethylaminoethoxyphenylmethyl-2-picoline
2-[a-(2-dimethylaminoethoxy)-a-methylbenzyl]pyridine
dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine
phenyl-2-pyridylmethyl-b-N,N-dimethylaminoethyl ether
所屬類別
原料藥:抗組胺藥

物理化學(xué)性質(zhì)

熔點25°C
沸點bp0.5 137-141°
密度1.0023 (rough estimate)
折射率1.5486 (estimate)
儲存條件-20°C Freezer, Under inert atmosphere
溶解度乙腈(微溶)、氯仿(微溶)、甲醇(微溶)
酸度系數(shù)(pKa)pKa 9.20(H2O t = 25 c = 0.002–0.01) (Uncertain);4.4 (Uncertain);9.2 (Uncertain)
形態(tài)Oil
顏色無色
穩(wěn)定性對溫度敏感
EPA化學(xué)物質(zhì)信息Doxylamine (469-21-6)

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H302-H315-H319-H335
毒害物質(zhì)數(shù)據(jù)469-21-6(Hazardous Substances Data)
毒性An antihistamine that formerly was used in pregnant women for antihistaminic and sedative properties. Although it has excellent sedative properties, it has been implicated in teratogenesis and in causing neurobehavioral toxicity and is therefore no longer used
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