35607-20-6
中文名稱(chēng)
阿夫立定
英文名稱(chēng)
Avridine
CAS
35607-20-6
分子式
C43H90N2O2
分子量
667.19
MOL 文件
35607-20-6.mol
35607-20-6 結(jié)構(gòu)式
基本信息
中文別名
阿夫立定 英文別名
AvridineCP-20961
2,2'-[[3-(Dioctadecylamino)propyl]imino]diethanol
2,2'-[[3-(Dioctadecylamino)propyl]imino]bisethanol
N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)propanediaMine
N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl)1,3-propanediamine
N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane
常見(jiàn)問(wèn)題列表
生物活性
CP-20961 是有效的、合成的無(wú)免疫原性的、可誘導(dǎo)關(guān)節(jié)炎的佐劑。體內(nèi)研究
Avridine-induced arthritis is severe and long lasting in LEW and DA rats.
CP-20961 (10 mg/kg, i.v., once either 24, 48, or 72 hours post-burn) had no effect on survival after challenge with
P. aeruginosa
96 hours post-burn.
Animal Model: | Female, Hartley-derived guinea pigs, weighing 350 to 400 g. |
Dosage: | 10 mg/kg. |
Administration: | IV once either 24, 48, or 72 hours post-burn. |
Result: | Had no effect on survival after challenge with P. aeruginosa 96 hours post-burn. |