33390-42-0
中文名稱
1,3,5,8-四羥基-2,4-雙(3-甲基-2-丁烯基)-9H-氧雜蒽-9-酮
英文名稱
1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9H-xanthen-9-one
CAS
33390-42-0
分子式
C23H24O6
分子量
396.43
MOL 文件
33390-42-0.mol
更新日期
2024/12/26 13:55:56
33390-42-0 結(jié)構(gòu)式
基本信息
中文別名
藤黃素藤黃苷
藤黃苷, 來(lái)源于山竹果
1,3,5,8-四羥基-2,4-雙(3-甲基-2-丁烯基)-9H-氧雜蒽…
1,3,5,8-四羥基-2,4-雙(3-甲基-2-丁烯基)-9H-氧雜蒽-9-酮
英文別名
gartaninAids098106
Aids-098106
Gartanin, 98%, from Garcinia mangostana L.
1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)xanthone
1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9h-xanthen-9-one
9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-
1,3,5,8-Tetrahydroxy-2,4-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one
9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-buten-1-yl)-
所屬類別
天然產(chǎn)物：氧雜蒽酮物理化學(xué)性質(zhì)
熔點(diǎn)167℃
沸點(diǎn)644.4±55.0 °C(Predicted)
密度1.326±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度氯仿：可溶
酸度系數(shù)(pKa)7.17±0.20(Predicted)
形態(tài)固體
顏色Light yellow to yellow
常見問(wèn)題列表
生物活性
Gartanin 是山竹果中的天然黃酮，具有抗氧化、抗炎、抗真菌、神經(jīng)保護(hù)和抗腫瘤作用。在人腦膠質(zhì)瘤細(xì)胞中，Gartanin 誘導(dǎo)細(xì)胞周期阻滯和自噬，抑制其遷移。體外研究
Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways .
Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells .