263251-78-1
263251-78-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T17000 英文別名
TavilermideGlycine, N-(2-hydroxy-5-nitrobenzoyl)-L-α-glutamyl-L-lysyl-L-homoseryl-, cyclic (1→3)-ether
3-((4S,7S,10S)-7-(4-aminobutyl)-4-((carboxymethyl)carbamoyl)-14-nitro-6,9,12-trioxo-3,4,5,6,7,8,9,10,11,12-decahydro-2H-benzo[b][1,5,8,11]oxatriazacyclotetradecin-10-yl)propanoic acid(WXG02263)
物理化學(xué)性質(zhì)
沸點1122.4±65.0 °C(Predicted)
密度1.341±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
酸度系數(shù)(pKa)3.59±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
水溶解性Water : 5 mg/mL (8.61 mM; adjust pH to 3-4 with HCl)
263251-78-1價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-17622 | 263251-78-1 Tavilermide | 263251-78-1 | 1mg | 1500元 |
| 2024/11/08 | HY-17622 | 263251-78-1 Tavilermide | 263251-78-1 | 5mg | 4000元 |
| 2024/08/19 | HY-17622 | 263251-78-1 Tavilermide | 263251-78-1 | 10mg | 6400元 |
常見問題列表
生物活性
Tavilermide 是一種選擇性的 TrkA 部分激動劑。靶點
TrkA
體外研究
Tavilermide (MIM-D3) is a tyrosine kinase TrkA receptor agonist, which can be used to treat dry eye.Tavilermide is a proteolytically stable, cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist. Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF.