2290635-22-0
中文名稱
MSR-RATIO
英文名稱
4H-1-Benzopyran-4-one, 2-[(1E)-2-[4-(methylsulfinyl)phenyl]ethenyl]-
CAS
2290635-22-0
分子式
C18H14O3S
分子量
310.37
MOL 文件
2290635-22-0.mol
2290635-22-0 結(jié)構(gòu)式
基本信息
中文別名
化合物MSR-RATIO 英文別名
Msr-greenMsr-Ratio
2-(4-(methylsulfinyl)styryl)-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-[(1E)-2-[4-(methylsulfinyl)phenyl]ethenyl]-
物理化學(xué)性質(zhì)
沸點522.7±50.0 °C(Predicted)
密度1.35±0.1 g/cm3(Predicted)
形態(tài)Solid
顏色White to off-white
常見問題列表
生物活性
Msr-Ratio (Msr-green)是一種比率型甲硫氨酸亞砜還原酶 (methionine sulfoxide reductase) 的熒光探針 (λex=375 nm, λem=550 nm)。Msr-Ratio 可用于監(jiān)測體外和活細(xì)胞中的甲硫氨酸亞砜還原酶活性。體外研究
Msr-Ratio is converted to its corresponding sulfide form by methionine sulfoxide reductase. Msr-Ratio displays favorable properties such as a nearly 400-fold fluorescence change, fast response rate (<30 min), large Stokes shift (120 nm), and green emission (550 nm).
There is a very weak background signal in live HL60 cells after the addition of Msr-Ratio. As the Msr-Ratio (10 μM) incubation time increased in cells from 0 to 8 h, the fluorescence signal constantly strengthened.