223568-55-6
223568-55-6 結(jié)構(gòu)式
基本信息
中文別名
(3S)-5-氟-3-[[(2S)-3-甲基-1-氧代-2-[[(苯基甲氧基)羰基]氨基]丁基]氨基]-4-氧代戊酸 英文別名
F 1013EP-1013
Z-VD-FMK (mixture of isomers)
(3S)-5-Fluoro-3-[[(2S)-3-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]butyl]amino]-4-oxopentanoic acid
Pentanoic acid, 5-fluoro-3-[[(2S)-3-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]butyl]amino]-4-oxo-, (3S)-
物理化學(xué)性質(zhì)
沸點(diǎn)639.8±55.0 °C(Predicted)
密度1.258±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : ≥ 60 mg/mL (156.91 mM)
酸度系數(shù)(pKa)3.92±0.19(Predicted)
形態(tài)Solid
顏色White to off-white
MX1013價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-10397 | MX1013 EP1013 | 223568-55-6 | 1 mg | 1100元 |
| 2024/11/08 | HY-10397 | MX1013 EP1013 | 223568-55-6 | 10mM * 1mLin DMSO | 1851元 |
| 2024/11/08 | HY-10397 | MX1013 EP1013 | 223568-55-6 | 5mg | 2200元 |
常見(jiàn)問(wèn)題列表
生物活性
EP1013 是一種廣譜的 caspase 選擇性抑制劑，可用于 1 型糖尿病研究。靶點(diǎn)
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Caspase
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體內(nèi)研究
EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversal rate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function.