217099-44-0
中文名稱
2-(氨基亞氨基甲基)苯并[B]噻吩-6-基 2-噻吩羧酸酯甲磺酸鹽 (1:1)
英文名稱
2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1)
CAS
217099-44-0
分子式
C15H14N2O5S3
分子量
398.47
MOL 文件
217099-44-0.mol
更新日期
2024/12/23 10:32:12
217099-44-0 結(jié)構(gòu)式
基本信息
中文別名
2-(氨基亞氨基甲基)苯并[B]噻吩-6-基 2-噻吩羧酸酯甲磺酸鹽 (1:1) 英文別名
BCX 1470BCX 1470
BCX-1470
BCX1470
BCX 1470 (Methanesulfonate)
2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-Thiophenecarbo
2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-Thiophenecarboxylic acid methanesulfonate
2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1)
2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1) ISO 9001：2015 REACH
所屬類別
有機原料：磺酸類氨基化合物物理化學(xué)性質(zhì)
儲存條件Keep in dark place,Sealed in dry,2-8°C
溶解度DMSO: ≥ 33.33 mg/mL (83.64 mM)
形態(tài)粉末
顏色White to off-white
常見問題列表
生物活性
BCX 1470 methanesulfonate 能抑制 factor D 和 C1s 的酯水解活性，IC50 分別為 96 nM 和 1.6 nM。靶點
IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin)
體外研究
BCX 1470 methanesulfonate is serine protease inhibitor. BCX 1470 methanesulfonate blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.