21516-68-7
中文名稱
紅曲
英文名稱
MONASCIN
CAS
21516-68-7
分子式
C21H26O5
分子量
358.43
MOL 文件
21516-68-7.mol
更新日期
2024/12/24 08:42:13
21516-68-7 結(jié)構(gòu)式
基本信息
中文別名
紅曲素功能性紅曲
紅曲素/紅曲霉素
英文別名
MONASCINCcris 9138
Monascoflavin
Monascin >=97.0% (HPLC)
(3S,3aR,9aR)-3-Hexanoyl-9a-methyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione
(3S)-3aα,4,8,9a-Tetrahydro-9aβ-methyl-3-(1-oxohexyl)-6-[(E)-1-propenyl]-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
(3S,3aR,9aR)-3a,4,8,9a-Tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione
2H-Furo[3,2-g][2]benzopyran-2,9(3H)-dione, 3a,4,8,9a-tetrahydro-9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propen-1-yl-, (3S,3aR,9aR)-
物理化學(xué)性質(zhì)
熔點(diǎn)145 °C
沸點(diǎn)574.6±50.0 °C(Predicted)
密度1.18±0.1 g/cm3(Predicted)
儲(chǔ)存條件2-8°C
酸度系數(shù)(pKa)10.59±0.60(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
BRN51355
InChIKeyXXKNHBAFFJINCK-RVEJDSBJSA-N
常見(jiàn)問(wèn)題列表
生物活性
Monascin 是可從紅曲米中提取得到的一種氮雜類色素，有口服活性，具有抗腫瘤和抗炎活性。Monascin 還能抑制NOR 的激活。體內(nèi)研究
Monascin (0.0025% in drinking water; mice) appears effective for the inhibition of UVB-initiated carcinogenesis on mouse skin.
| Animal Model: | SENCAR mouse using a UVB irradiation as an initiator and TPA as a promoter. |
| Dosage: | 0.0025% in drinking water. |
| Administration: | Orally daily for 2 weeks in drinking water. |
| Result: | Reduced the number of the papillomas. |