2130750-59-1
2130750-59-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T14285 英文別名
AN11251Acetic acid, 2-[(7-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-6-yl)oxy]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
應(yīng)用領(lǐng)域
用途一
AN11251 is a potenet Anti-Wolbachia Agent with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis (EC50 = 1.5nM for LDW1 cell lines and 15 nM for C6/36 cell lines). AN11251 showed in vitro anti-Wolbachia activity and physicochemical and pharmacokinetic properties providing high exposure in plasma.