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211813-86-4

中文名稱 211813-86-4
英文名稱 Eniporide hydrochloride
CAS 211813-86-4
分子式 C14H17ClN4O3S
分子量 356.83
MOL 文件 211813-86-4.mol
211813-86-4 結(jié)構(gòu)式 211813-86-4 結(jié)構(gòu)式

基本信息

中文別名
化合物 ENIPORIDE HYDROCHLORIDE
英文別名
Eniporide hydrochloride

物理化學(xué)性質(zhì)

儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO: ≥ 150 mg/mL (420.37 mM)
形態(tài)Solid
顏色White to off-white
211813-86-4價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-106150B211813-86-4
Eniporide hydrochloride
211813-86-45mg990元
2024/11/08HY-106150B211813-86-4
Eniporide hydrochloride
211813-86-410mM * 1mLin DMSO1089元
2024/11/08HY-106150B211813-86-4
Eniporide hydrochloride
211813-86-410mg1750元

常見問題列表

生物活性
Eniporide hydrochloride (EMD-96785 hydrochloride)是有效地 Na+/H+ 交換抑制劑。
靶點(diǎn)

Sodium Channel

體外研究

There is no significant effects of the Na + /H + exchange inhibitor eniporide on cardiac performance and high energy phosphate content in healthy pig hearts subjected to ischemia/reperfusion induced by crystalloid cardioplegic arrest.

體內(nèi)研究

In stage 1, the administration of 100 mg and 150 mg eniporide results in smaller infarct sizes, especially in the angioplasty group. In contrast, in stage 2 there is no difference in the enzymatic infarct size between the three groups. Overall there is no effect of eniporide on clinical outcome (death, cardiogenic shock, heart failure, life-threatening arrhythmias). However, there is a significant reduction of the incidence of heart failure in patients reperfused late (>4 h).

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