天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

返回ChemicalBook首頁>CAS數(shù)據(jù)庫列表>211735-76-1

211735-76-1

中文名稱 CX691
英文名稱 FARAMPATOR
CAS 211735-76-1
分子式 C12H13N3O2
分子量 231.25
MOL 文件 211735-76-1.mol
更新日期 2024/12/03 15:40:35
211735-76-1 結構式 211735-76-1 結構式

基本信息

中文別名
化合物FARAMPATOR
英文別名
CX 691
Org2444
Org 24448
FARAMPATOR
CX-691
ORG2444
Org24448, CX-691
Farampator (CX691)
CX 691
ORG 24448
CX-691
CX691
Methanone, 2,1,3-benzoxadiazol-5-yl-1-piperidinyl-
所屬類別
生物化工:激動劑抑制劑

物理化學性質

沸點398.3±34.0 °C(Predicted)
密度1.299±0.06 g/cm3(Predicted)
儲存條件Sealed in dry,Store in freezer, under -20°C
溶解度DMF: 30 mg/ml; DMF:PBS (pH7.2) (1:40): 25μg/ml; DMSO: 20 mg/ml
酸度系數(shù)(pKa)-1.33±0.36(Predicted)
形態(tài)結晶固體
顏色White to off-white

常見問題列表

生物活性
Farampator (CX-691;Org24448) 是一種AMPA受體正調節(jié)劑。
體內研究

Farampator has potential in treating disorders characterised by cognitive deficits such as Alzheimer's disease and schizophrenia. CX691 attenuates a scopolamine-induced impairment of cued fear conditioning following acute administration (0.1 mg/kg p.o.) and a temporally induced deficit in novel object recognition following both acute (0.1 and 1.0 mg/kg p.o.) and sub-chronic (bi-daily for 7 days) administration (0.01, 0.03, 0.1 mg/kg p.o.). It also improves attentional set-shifting following sub-chronic administration (0.3 mg/kg p.o.). Farampator (500 mg) unequivocally improves short-term memory but appeares to impair episodic memory. Furthermore, it tends to decrease the number of switching errors in the CTMT. Drug-induced side effects (SEs) included headache, somnolence and nausea. Subjects with SEs has significantly higher plasma levels of farampator than subjects without SEs.

"211735-76-1" 相關產(chǎn)品信息