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2056-98-6

中文名稱 2'-脫氧胞苷三磷酸
英文名稱 2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
CAS 2056-98-6
分子式 C9H16N3O13P3
分子量 467.16
MOL 文件 2056-98-6.mol
2056-98-6 結構式 2056-98-6 結構式

基本信息

中文別名
2'-脫氧胞苷三磷酸
2'-脫氧胞苷 5'-三磷酸酯
((2R,3S,5R)-5-(4-氨基-2-氧代嘧啶-1(2H)-基)-3-羥基四氫呋喃-2-基)甲基四氫三磷酸
英文別名
5'-DCTP
DCTP, LI
Deoxy-CTP
((2R,3S,5R)
DCTP LI-SALT
Deoxy-5'-CTP
dCTP.Free Acid
dCTP - 100mmol solution
deoxycytidine-triphosphate
2'-deoxycytidine triphosphate
所屬類別
生物化工:核苷酸及其類似物

物理化學性質

沸點811.5±75.0 °C(Predicted)
密度2.38±0.1 g/cm3(Predicted)
儲存條件Sealed in dry,Room Temperature
酸度系數(shù)(pKa)0.80±0.50(Predicted)
形態(tài)水溶液穩(wěn)定
顏色White to off-white
水溶解性Water : ≥ 35 mg/mL (74.92 mM)

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H302-H315-H319-H335

常見問題列表

生物活性
Deoxycytidine triphosphate (dCTP) 是可用于 DNA 合成 (DNA synthesis) 的核苷三磷酸。Deoxycytidine triphosphate 可用于實時 PCR,cDNA 合成 和 DNA 測序等研究。
靶點

Human Endogenous Metabolite

體外研究

Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.

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