天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

返回ChemicalBook首頁>CAS數(shù)據(jù)庫列表>2026635-66-3

2026635-66-3

中文名稱 GNE 5729
英文名稱 (1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE
CAS 2026635-66-3
分子式 C17H10Cl2F3N5O
分子量 428.2
MOL 文件 2026635-66-3.mol
2026635-66-3 結(jié)構(gòu)式 2026635-66-3 結(jié)構(gòu)式

基本信息

中文別名
化合物 T15408
英文別名
GNE 5729
(1R,2R)-2-(7-CHLORO-2-((5-CHLORO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)METHYL)-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-6-YL)CYCLOPROPANE-1-CARBONITRILE

物理化學(xué)性質(zhì)

沸點(diǎn)527.6±60.0 °C(Predicted)
密度1.71±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)0.89±0.70(Predicted)
形態(tài)Solid
顏色White to yellow

應(yīng)用領(lǐng)域

用途一
GNE-5729 is a potent and selective NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. GNE-5729 had a very selective profile against various off-target ion channels with greater than a 100-fold selectivity over other NMDAR subtypes and greater than a 1000-fold selectivity over AMPAR. The improved pharmacokinetic profile and AMPAR selectivity make GNE-5729 a superior tool compound compare to GNE-0723 for testing the efficacy and safety of GluN2A potentiation.
"2026635-66-3" 相關(guān)產(chǎn)品信息