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1980884-01-2

中文名稱 化合物 PI3KΔ/Γ-IN-1
英文名稱 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[3-[(4-hydroxy-1-piperidinyl)sulfonyl]phenyl]amino]-5,8,11-trimethyl-
CAS 1980884-01-2
分子式 C25H28N6O4S
分子量 508.59
MOL 文件 1980884-01-2.mol
1980884-01-2 結(jié)構(gòu)式 1980884-01-2 結(jié)構(gòu)式

基本信息

英文別名
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[3-[(4-hydroxy-1-piperidinyl)sulfonyl]phenyl]amino]-5,8,11-trimethyl-

物理化學(xué)性質(zhì)

沸點(diǎn)786.1±70.0 °C(Predicted)
密度1.399±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)14.44±0.20(Predicted)
形態(tài)Solid
顏色Off-white to gray

應(yīng)用領(lǐng)域

用途一
FMF-02-063-1 inhibits p308 AKT and p473 AKT signaling in isogenic HMEC cell lines where PI3K signaling is driven exclusively by CA-p110-δ under serum starved conditions. FMF-02-063-1 does not inhibit p308 AKT and p473 AKT signaling in isogenic HMEC cell lines where PI3K signaling is driven exclusively by CAp110-α or CA-p110-β.
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