195966-93-9
195966-93-9 結(jié)構(gòu)式
基本信息
(rel)-Asperparaline A
Spiro[5H,6H-5a,9a-(iminomethano)-1H-cyclopent[f]indolizine-7(8H),3'-pyrrolidine]-2',5',10-trione, tetrahydro-1,1',8,8,11-pentamethyl-, (1R,3'R,5aR,8aR,9aS)-rel-(-)-
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-124874 | 曲霉酰亞胺 (rel)-Asperparaline A | 195966-93-9 | 5mg | 8748元 |
常見問題列表
Asperparaline A (1 μM; 1 min) markedly and reversibly blocks the acetylcholine (Ach; 10 μM)-induced current in the silkworm larval neurons.
Asperparaline A (1-1000 nM; 1 min) differentially blocks the peak and slowly desensitizing currents, with IC
50
s of 20.2 and?39.6 nM, respectively.
Asperparaline A (10 μM; 1 min) reduces the peak current amplitude of the ACh (100 μM)-induced response of α3β4 nAChR by 33.4%, while barely influencing the amplitudes of the responses to ACh of the α4β2 and α7 nAChRs in
X. laevis
oocytes.
Asperparaline A (10 μg/g; p.o.) exhibits paralysis against silk worms within 1 h and lasts for 7 to 10 h.
Asperparaline A (3 μg/g; injection with a micro-syringe) exhibits paralysis activity against silk worms within 20 min and lasts for 4 to 5 h.