1944-12-3
中文名稱
氫溴酸非諾特羅
英文名稱
FENOTEROL HYDROBROMIDE
CAS
1944-12-3
分子式
C17H22BrNO4
分子量
384.26
MOL 文件
1944-12-3.mol
更新日期
2024/08/19 16:52:47
1944-12-3 結(jié)構(gòu)式
基本信息
中文別名
氫溴酸芬忒醇氫溴酸非諾特羅
氫溴酸菲諾特羅
菲諾特洛氫溴酸鹽
氫溴酸非諾特羅 標(biāo)準(zhǔn)品
氫溴酸菲諾特羅標(biāo)準(zhǔn)溶液
甲醇中菲諾特羅溶液標(biāo)準(zhǔn)物質(zhì)
非諾特羅峰鑒別 EP標(biāo)準(zhǔn)品
氫溴酸非諾特羅 EP標(biāo)準(zhǔn)品
氫溴酸非諾特羅/酚丙喘寧芬忒醇
英文別名
AirumEmitex
Ugacor
berotec
th1165a
Siobetec
Dosberotec
partusisten
FENOTEROL HBR
fenoterolbromide
所屬類別
原料藥：平喘藥
氫溴酸非諾特羅價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-B0976A | 氫溴酸非諾特羅 Fenoterol hydrobromide | 1944-12-3 | 100mg | 700元 |
| 2024/11/08 | HY-B0976A | 氫溴酸非諾特羅 Fenoterol hydrobromide | 1944-12-3 | 10mM * 1mLin DMSO | 930元 |
| 2024/11/08 | S5768 | 氫溴酸非諾特羅 Fenoterol hydrobromide | 1944-12-3 | 25mg | 794.63元 |
常見問題列表
生物活性
Fenoterol hydrobromide (Phenoterol)是fenoterol的氫溴酸鹽。Fenoterol是β2 adrenoreceptor激動劑，具有支氣管擴張活性。靶點
| Target | Value |
|
β2 adrenoreceptor
() |
體外研究
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.
Western Blot Analysis
| Cell Line: | THP-1 cells stimulated with AICAR |
| Concentration: | 1 μM |
| Incubation Time: | Pre-incubated 30 minutes |
| Result: | Significantly downregulated the elevated phosphorylation levels of AMPK. |
體內(nèi)研究
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
| Animal Model: | Male C57BL/6J mice (6 weeks old) with neuropathy |
| Dosage: | 0.7 mg/kg |
| Administration: | Intraperitoneal injection; twice a day; for 3 weeks |
| Result: | Alleviated neuropathic allodynia during chronic treatment. |