1800487-55-1
1800487-55-1 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點670.3±55.0 °C(Predicted)
密度1.31±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)14.46±0.46(Predicted)
形態(tài)Solid
顏色White to light yellow
應(yīng)用領(lǐng)域
用途一
OT-82 is a potent NAMPT Inhibitor that targets the strong dependence of hematological malignancies on NAD biosynthesis. OT-82 showed strong efficacy against hematopoietic malignancies including acute myeloblastic and lymphoblastic adult and pediatric leukemias, erythroleukemia, multiple myeloma, and Burkitt's lymphoma in vitro and in mouse xenograft models.