175873-26-4
中文名稱
(6R)-HYDROXY (R,S)-PALONOSETRON
英文名稱
(6R)-Hydroxy (R,S)-Palonosetron
CAS
175873-26-4
分子式
C19H24N2O2
分子量
312.406
MOL 文件
175873-26-4.mol
175873-26-4 結(jié)構(gòu)式
基本信息
中文別名
帕洛諾司瓊雜質(zhì)46RS-帕洛諾司瓊6R-羥基雜質(zhì)
英文別名
Palonosetron Impurity 46(6R)-Hydroxy (R,S)-Palonosetron
(3aR,6R)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-6-hydroxy-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one
應(yīng)用領(lǐng)域
用途一
(6R)-Hydroxy (S,R)-Palonosetron is a stereoisomer of (6S)-Hydroxy (S,S)-Palonosetron (H949365). (6S)-Hydroxy (S,S)-Palonosetron (H949365) is a metabolite of Palonosetron (P165800, HCl salt) which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting.