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1672672-26-2

英文名稱 3-Pyridinecarboxylic acid, 1-[2-[[(E)-[(2',4'-dichloro[1,1'-biphenyl]-2-yl)methylene]amino]oxy]ethyl]-1,2,5,6-tetrahydro-, hydrochloride (1:1)
CAS 1672672-26-2
分子式 C21H21Cl3N2O3
分子量 455.76
MOL 文件 1672672-26-2.mol
1672672-26-2 結(jié)構(gòu)式 1672672-26-2 結(jié)構(gòu)式

基本信息

英文別名
3-Pyridinecarboxylic acid, 1-[2-[[(E)-[(2',4'-dichloro[1,1'-biphenyl]-2-yl)methylene]amino]oxy]ethyl]-1,2,5,6-tetrahydro-, hydrochloride (1:1)

應(yīng)用領(lǐng)域

用途一
DDPM-2571 is a highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties. DDPM-2571 was quickly distributed into the brain and was highly effective in the prevention of chemically-induced seizures (pentylenetetrazole and pilocarpine models) and 6-Hz convulsions. It demonstrated significant anxiolytic-like and antidepressant-like properties. DDPM-2571 had antinociceptive properties, both in the hot plate test and in the second phase of the formalin test.
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