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167006-13-5

中文名稱 化合物 T27743
英文名稱 1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-
CAS 167006-13-5
分子式 C25H23N7O3S
分子量 501.56
MOL 文件 167006-13-5.mol
167006-13-5 結(jié)構(gòu)式 167006-13-5 結(jié)構(gòu)式

基本信息

中文別名
化合物 T27743
英文別名
WK1492
WK-1492
WK14922K
WK-14922K
KRH-594 free acid
1-Cyclopentene-1-carboxylic acid, 2-[[[5-ethyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3,4-thiadiazol-2(3H)-ylidene]amino]carbonyl]-

應(yīng)用領(lǐng)域

用途一
KRH-594, also known as WK-1492; WK-14922K, is a potent, specific and insurmountable AT1 receptor antagonist. KRH-594 prevents end-organ damage in stroke-prone spontaneously hypertensive/Izm rats. KRH-594 ameliorates nephropathy and hyperlipidaemia in diabetic spontaneously hypertensive rats.
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