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1643809-54-4

英文名稱 5-[(2R)-2-[4-(5-aminopyrazin-2-yl)phenyl]oxolan-2-yl]-N-(2-hydroxy-2-methylpropyl)pyridine-2-carboxamide
CAS 1643809-54-4
分子式 C24H27N5O3
分子量 433.503
MOL 文件 1643809-54-4.mol
1643809-54-4 結(jié)構(gòu)式 1643809-54-4 結(jié)構(gòu)式

基本信息

英文別名
5-[(2R)-2-[4-(5-aminopyrazin-2-yl)phenyl]oxolan-2-yl]-N-(2-hydroxy-2-methylpropyl)pyridine-2-carboxamide

應(yīng)用領(lǐng)域

用途一
AZD6642 is a potential and selective 5-Lipoxygenase activating Protein (FLAP) inhibitor. AZD6642 shows high specific potency and low lipophilicity resulting in a selective and metabolically stable profile. Based on initial PK/PD relations a low dose to human was predicted.
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