1614225-93-2
1614225-93-2 結(jié)構(gòu)式
基本信息
中文別名
化合物 T12453 英文別名
PHT-7.31(2H)-Phthalazinone, 4-(1,3-dioxan-2-ylmethyl)-2-[[4-(4-methylphenyl)-2-thiazolyl]methyl]-
物理化學性質(zhì)
沸點629.2±65.0 °C(Predicted)
密度1.35±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度DMSO: 62.5 mg/mL (144.17 mM)
酸度系數(shù)(pKa)2.00±0.10(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
應用領域
用途一
PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, which inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling.