1597439-87-6
中文名稱
化合物 T26894
英文名稱
BRD0209
(BRD 0209)
CAS
1597439-87-6
分子式
C22H25N3O
分子量
347.45
MOL 文件
1597439-87-6.mol
1597439-87-6 結(jié)構(gòu)式
基本信息
中文別名
化合物 T26894 英文別名
BRD0209BRD0209 (BRD 0209)
5H-Pyrazolo[3,4-b]quinolin-5-one, 3-cyclopropyl-1,2,4,6,7,8-hexahydro-4,7,7-trimethyl-4-phenyl-, (4S)-
所屬類別
材料化學(xué)：配體應(yīng)用領(lǐng)域
用途一
BRD0209 is a highly selective and potent GSK3 inhibitor. BRD0209 demonstrates in vivo efficacy in a dopaminergic signaling paradigm modeling mood-related disorders. The mood stabilizer lithium, the first-line treatment for bipolar disorder, is hypothesized to exert its effects through direct inhibition of glycogen synthase kinase 3 (GSK3).