145854-59-7
基本信息
MASTOPARAN 7
INLKALAALAKALL-NH2
Mastoparan-7, ≥97% (HPLC)
MASTOPARAN 7 SYNTHETIC >98%
mastoparan from polistes jadwagae
MAS 7 - CAS 145854-59-7 - Calbiochem
Mastoparan-7 >=97% (HPLC), lyophilized powder
19: PN: WO2010069074 SEQID: 17 claimed protein
ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2
物理化學性質(zhì)
報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
2024/01/25 | HY-P0258 | ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2 Mas7 | 145854-59-7 | 1mg | 900元 |
2024/01/25 | HY-P0258 | ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2 Mas7 | 145854-59-7 | 5mg | 3600元 |
2024/01/25 | HY-P0258 | ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-ALA-LEU-LEU-NH2 Mas7 | 145854-59-7 | 10mg | 5600元 |
常見問題列表
Mas7 (Mastoparan 7) produces several biological effects in different cell types. The effect of Mas7 on endogenous mono-ADP-ribosyltransferase activity is in the micromolar range with a maximal activation of 205% over the basal. In pertussis treated plasma membranes, it is found that the effect of Mas7 on endogenous mono-ADP-ribosyltransferase is partially blocked, which suggests the involvement of G-proteins, such as Gi or G0.
Mas7 is a basic tetradecapeptide isolated from isp venom, which activates guanine nucleotide-binding regulatory proteins (G-proteins) and stimulates apoptosis. In smooth muscle cells, Mas7 leads to an increase in the perfusion pressure. Vascular contraction is induced by Mas7. The vasoconstriction triggered by mas-7 exhibited a slower increase compared to that simulated by phenylephrine or vasopressin.
Exposure of hippocampal neurons to a low dose of Mas-7 increases dendritic spine density and spine head width in a time-dependent manner. Additionally, Mas-7 enhances postsynaptic density protein-95 (PSD-95) clustering in neurites and activates Gαo signaling, increasing the intracellular Ca
2+
concentration.