1366000-58-9
基本信息
物理化學(xué)性質(zhì)
報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
2022/04/29 | HY-P1235A | ATRIAL NATRIURETIC PEPTIDE (ANP) (1-28), HUMAN, PORCINE ACETATE Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate | 1366000-58-9 | 500μg | 1800元 |
2022/04/29 | HY-P1235A | ATRIAL NATRIURETIC PEPTIDE (ANP) (1-28), HUMAN, PORCINE ACETATE Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate | 1366000-58-9 | 1mg | 2800元 |
2022/04/29 | HY-P1235A | ATRIAL NATRIURETIC PEPTIDE (ANP) (1-28), HUMAN, PORCINE ACETATE Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate | 1366000-58-9 | 5mg | 9800元 |
常見問題列表
Endothelin-1
Atrial natriuretic peptide (ANP) is a diuretic, natriuretic, and vasodilatory peptide hormone originally isolated from mammalian hearts. In cultured porcine endothelial cells the inhibition by porcine ANP (1-28) of immunoreactive endothelin-1 secretion after stimulation with Angiotensin II (Ang II) is paralleled by an increase in the cellular cGMP level. Porcine ANP (1-28) strongly inhibits immunoreactive endothelin-1 secretion in porcine aorta after stimulation with Ang II. ANP is a cardiac hormone involved in electrolyte and fluid homeostasis. The inhibition by ANP of endothelin-1 secretion stimulated by angiotensin II (ANGII) and thrombin using cultured human umbilical-vein endothelial cells. Human ANP (1-28) inhibits immunoreactive (ir)-endothelin-1 secretion and increases cyclic GMP in the human umbilical-vein endothelial cells. In glomeruli from normal rats, Human 125 I-ANP (1-28) binds to a single population of high affinity receptors with a mean equilibrium dissociation constant of 0.46 nM. Human ANP (1-28) binds to the glomerular ANP receptor with high affinity stimulated cGMP accumulation. Human ANP (1-28) markedly stimulates cGMP generation, but not cAMP generation in normal rat glomeruli.