1362911-19-0
1362911-19-0 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
密度1.32±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度可溶于DMSO
酸度系數(shù)(pKa)7.05±0.46(Predicted)
形態(tài)Solid
顏色White to off-white
應(yīng)用領(lǐng)域
用途一
ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significantly increase cell death in Multiple Myeloma (MM) cell lines and primary cells, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.