133943-59-6
中文名稱
H-LEU-ARG-PRO-OH
CAS
133943-59-6
分子式
C17H32N6O4
分子量
384.47
MOL 文件
133943-59-6.mol
更新日期
2024/12/16 10:25:30
133943-59-6 結(jié)構(gòu)式
基本信息
中文別名
L-亮氨酰-L-精氨酰-L-脯氨酸 英文別名
LRPLeu-Arg-Pro
H-LEU-ARG-PRO-OH
LHRH 7-9 SEQUENCE
Leucylarginylproline
H-LEU-ARG-PRO-OH 2HCL
LHRH (7-9) SEQUENCE 2HCL
L-Proline,L-leucyl-L-arginyl-
常見問題列表
生物活性
Leucylarginylproline是血管緊張素轉(zhuǎn)換酶 (ACE) 抑制劑，IC50值為0.27μM。靶點(diǎn)
IC50: 0.27μM (ACE)
體外研究
Intravenous injection of Leucylarginylproline (30mg/kg) causes a decrease in the blood pressure. The maximum mean blood pressure reduction (about 15 mmHg) occurrs about 2 min after the injection. Leucylarginylproline peptide reduces the blood pressure by about 15 mmHg at the fourth hour and shows a maximal reduction effect of about 35 mmHg at the eighth hour after oral administration.