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133161-96-3

中文名稱 PGD-M
英文名稱 PGD-M
CAS 133161-96-3
分子式 C16H24O7
分子量 328.36
MOL 文件 133161-96-3.mol
133161-96-3 結(jié)構(gòu)式 133161-96-3 結(jié)構(gòu)式

基本信息

英文別名
PGDM
TETRANOR-PGDM
TETRANOR-PROSTAGLANDIN D METABOLITE
(Z)-9α-11β-dihydroxy-15-oxo-2,3,18.19-tetranorprost-5-ene-1,20-dioic acid
Cyclopentanehexanoic acid, 2-[(2Z)-4-carboxy-2-buten-1-yl]-3,5-dihydroxy-γ-oxo-, (1R,2R,3S,5S)-

物理化學(xué)性質(zhì)

儲存條件-20°C儲存
溶解度DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

應(yīng)用領(lǐng)域

用途一
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2.
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