130357-25-4
中文名稱
艾塞那肽
英文名稱
EXENDIN-3
CAS
130357-25-4
分子式
C184H282N50O61S
分子量
4202.57
MOL 文件
130357-25-4.mol
更新日期
2025/01/07 10:42:00
130357-25-4 結(jié)構(gòu)式
基本信息
中文別名
生物活性肽EXENDIN 3 英文別名
EXENDIN-3Exendin-3 >=97%
EXENDIN-3 USP/EP/BP
M.W. 4202.57 C184H282N50O61S
HSDGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
HIS-SER-ASP-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2
HIS-SER-ASP-GLY-THR-PHE-THR-SER-ASP-LEU-SER-LYS-GLN-MET-GLU-GLU-GLU-ALA-VAL-ARG-LEU-PHE-ILE-GLU-TRP-LEU-LYS-ASN-GLY-GLY-PRO-SER-SER-GLY-ALA-PRO-PRO-PRO-SER-NH2: HSDGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
所屬類別
生物化工：多肽常見問題列表
生物活性
Exendin-3是從吉拉怪獸蜥蜴 Heloderma horridurn 毒液分離的生物活性肽。靶點(diǎn)
VIP receptor, putative exendin receptor
體外研究
Exendin-3 interacts with at least two receptors on guinea pig pancreatic acini; at high concentrations (>100 nM) the peptide interacts with VIP receptors, thereby causing a large increase in cAMP and stimulating amylase release; at lower concentrations (0.1-3 nM) the peptide interacts with a putative exendin receptor, thereby causing a smaller increase in cAMP of undetermined function.