1257116-00-9
中文名稱
化合物 T24738
英文名稱
RQ-00311651
CAS
1257116-00-9
分子式
C19H18F3N5O2
分子量
405.37
MOL 文件
1257116-00-9.mol
1257116-00-9 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
RQ-00311651 is a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain. RQ-00311651 strongly suppressed T currents when tested at holding potentials of -65 ～ -60 mV, but not -80 mV, in the Cav3.1- or Cav3.2-expressing cells. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.