1135280-28-2
中文名稱
KN-92 磷酸鹽
英文名稱
KN92 phosphate
CAS
1135280-28-2
分子式
C24H28ClN2O7PS
分子量
554.98
MOL 文件
1135280-28-2.mol
更新日期
2024/12/23 17:38:45
1135280-28-2 結(jié)構(gòu)式
基本信息
中文別名
KN-92 磷酸鹽KN92 游離和鹽酸鹽
英文別名
CS-1093KN92-H3PO4
KN 92
KN92
KN92 phosphate
KN 92 phosphate
KN-92 (phosphate)
物理化學(xué)性質(zhì)
儲存條件= -70C
溶解度≥25 mg/mL in DMSO; insoluble in H2O; ≥43.1 mg/mL in EtOH with gentle warming
形態(tài)粘稠液體
顏色White to off-white
常見問題列表
生物活性
KN-92是KN-93的非活化派生物，KN-93是CaMKII的選擇性抑制劑。體外研究
KN-93 (5-50 μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth.
The analysis of cell cycle regulator expression reveals that KN-93 rather than KN-92 reduced the expression of p53 and p21.
Cell Viability Assay
| Cell Line: | Human hepatic stellate cells (LX-2) |
| Concentration: | 5-50 μM |
| Incubation Time: | 24 hours |
| Result: | Ineffective in blocking cell growth. |