109358-46-5
中文名稱(chēng)
BOC-LEU-ARG-ARG-AMC · 2 HCL
英文名稱(chēng)
Boc-Leu-Arg-Arg-AMC . 2 HCl
CAS
109358-46-5
分子式
C33H52N10O7
分子量
700.83
MOL 文件
109358-46-5.mol
更新日期
2024/12/16 10:25:31
109358-46-5 結(jié)構(gòu)式
基本信息
英文別名
Boc-LRR-AMCBoc-Leu-Arg-Arg-AMC . 2 HCl
N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide
tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-(4-methyl-2-oxochromen-7-yl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
所屬類(lèi)別
生物化工：氨基酸應(yīng)用領(lǐng)域
用途一
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitatioemission maxima of 340-360/440-460 nm, respectively.