108351-91-3
中文名稱(chēng)
化合物 T28319
英文名稱(chēng)
PD 120697
CAS
108351-91-3
分子式
C11H15N3S
分子量
221.32
MOL 文件
108351-91-3.mol
108351-91-3 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
PD 120697 is a dopamine antagonist. It is a novel class of compounds with central dopamine agonist properties. It has been identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests that include [3H]-haloperidol and [3H]-N-propylnorapomorphine binding, inhibition of striatal DA synthesis, inhibition of DA neuronal firing, inhibition of spontaneous locomotor activity, and reversal of reserpine-induced depression in rats.