108226-05-7
中文名稱(chēng)
108226-05-7
英文名稱(chēng)
Benzamide, 4-amino-5-chloro-2-propoxy-N-[1-[3-(tetrahydro-2-furanyl)propyl]-4-piperidinyl]-
CAS
108226-05-7
分子式
C22H34ClN3O3
分子量
423.98
MOL 文件
108226-05-7.mol
108226-05-7 結(jié)構(gòu)式
基本信息
中文別名
化合物 T13570 英文別名
BENZAMIDE DERIVATIVE 1Benzamide, 4-amino-5-chloro-2-propoxy-N-[1-[3-(tetrahydro-2-furanyl)propyl]-4-piperidinyl]-
常見(jiàn)問(wèn)題列表
生物活性
Benzamide Derivative 1 是來(lái)自專(zhuān)利 EP0213775A1，化合物 18，的苯甲酰胺衍生物。Benzamide Derivative 1 有潛力用于胃腸疾病的研究。靶點(diǎn)
Dopamine, mACh receptor
體外研究
Substituted benzamides have been shown to possess a number of pharmacological properties most of which are related to their ability to antagonize the central and peripheral effects of dopamine and/or facilitate the release of acetylcholine on to muscarinic receptors in the gastrointestinal smooth muscle. This has led to their successful clinical use as antiemetic and in the treatment of a wide range of gastrointestinal disorders of somatic, psychosomatic and iatrogenic origin.