107767-58-8
107767-58-8 結(jié)構(gòu)式
基本信息
中文別名
化合物 T14075 英文別名
A 8027151H-Purine-2,6-dione, 3,7-dihydro-1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propyl-
物理化學(xué)性質(zhì)
沸點(diǎn)526.7±56.0 °C(Predicted)
密度1.22±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO: 190 mg/mL (589.33 mM)
酸度系數(shù)(pKa)15.28±0.29(Predicted)
形態(tài)Solid
顏色White to off-white
107767-58-8價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-U00142 | 107767-58-8 A-802715 | 107767-58-8 | 1mg | 1600元 |
| 2024/11/08 | HY-U00142 | 107767-58-8 A-802715 | 107767-58-8 | 10mM * 1mLin DMSO | 2270元 |
| 2024/11/08 | HY-U00142 | 107767-58-8 A-802715 | 107767-58-8 | 5mg | 3200元 |
常見(jiàn)問(wèn)題列表
生物活性
A802715 是一種甲基黃嘌呤衍生物，TD50為 0.9-1.1 mM。體外研究
The toxicity of the methylxanthine derivative A802715 is determined against the two human melanoma lines, Be11 and MeWo, and against the two human squamous cell carcinoma lines, 4197 and 4451, by vital dye staining assay. A802715 has a TD 50 of 0.9-1.1 mM and is the most toxic. In p53 wt cells BrdU incorporations show that the irradiation-induced suppression of S-phase entry is strongly enhanced by A802715. A802715 prolongs the G 2 /M block or remain ineffective depending on the p53 status of the cell line.