107429-63-0
107429-63-0 結(jié)構(gòu)式
基本信息
中文別名
林托必利 英文別名
LintoprideBenzamide, 4-amino-5-chloro-N-[(1-ethyl-4,5-dihydro-1H-imidazol-2-yl)methyl]-2-methoxy-
物理化學性質(zhì)
沸點494.1±45.0 °C(Predicted)
密度1.35±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)13.20±0.46(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
常見問題列表
生物活性
Lintopride是 5HT4 拮抗劑，對5HT3 有輕微拮抗作用。靶點
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5-HT 4 Receptor
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5-HT 3 Receptor
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體外研究
Lintopride significantly increases the lower oesophageal sphincter basal tone without affecting lower oesophageal sphincter physiological relaxation after swallowing. Peristaltic waves are also enhanced by Lintopride.