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ChemicalBook--->CAS DataBase List--->99196-74-4

99196-74-4

99196-74-4 Structure

99196-74-4 Structure
IdentificationBack Directory
[Name]

ACA
[CAS]

99196-74-4
[Synonyms]

ACA
ACL
AMARANTHUS CAUDATUS LECTIN
GAMRBCZMOOMBSQ-CCEZHUSRSA-N
N-(4-Pentylcinnamoyl)anthranilic acid
N-(p-Amylcinnamoyl)anthranilic acid >=98% (HPLC)
2-[3-(4-pentylphenyl)prop-2-enoylamino]benzoic acid
2-[[1-oxo-3-(4-Pentylphenyl)-2-propen-1-yl]amino]-benzoic acid
[Molecular Formula]

C21H23NO3
[MDL Number]

MFCD01321668
[MOL File]

99196-74-4.mol
[Molecular Weight]

337.41
Chemical PropertiesBack Directory
[storage temp. ]

room temp
[solubility ]

DMSO: ≥20mg/mL
[form ]

powder
[color ]

white to off-white
Safety DataBack Directory
[Hazard Codes ]

N
[Risk Statements ]

50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

N-(p-Amylcinnamoyl)anthranilic acid has been used as a transient receptor potential cation channel subfamily M member 2 (TRPM2) inhibitor, in studying its role in regulating the production of reactive oxygen species (ROS).
[Definition]

ChEBI: N-(p-amylcinnamoyl)anthranilic acid is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 4-pentylcinnamoyl group. It is a transient receptor potential (TRP) channel blocker and phospholipase A2 (PLA2) inhibitor. It has a role as an EC 3.1.1.4 (phospholipase A2) inhibitor and a TRP channel blocker. It is an amidobenzoic acid, a member of cinnamamides and a secondary carboxamide.
[General Description]

N-(p-Amylcinnamoyl)anthranilic acid (ACA) functions as a broad spectrum phospholipase A2 inhibitor and blocks transient receptor potential (TRP) channels. It inhibits calcium activated chloride current in cardiac ventricular myocytes. ACA regulates various ion channels.
[Biochem/physiol Actions]

Broad spectrum phospholipase A2 (PLA2) inhibitor and TRP channel blocker.
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