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ChemicalBook--->CAS DataBase List--->98224-03-4

98224-03-4

98224-03-4 Structure

98224-03-4 Structure
IdentificationBack Directory
[Name]

1-(2,3-DIHYDRO-1,4-BENZODIOXIN-5-YL)-PIPERAZINE HYDROCHLORIDE
[CAS]

98224-03-4
[Synonyms]

DU-28853
EltoprazineHCl
Eltoprazine (DU-28853)
ELTOPRAZINE HYDROCHLORIDE
5-Piperazino-2,3-dihydro-1,4-benzodioxin
5-(Piperazin-1-yl)-2,3-dihydro-1,4-benzodioxin
N-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)piperazine
4(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine
1-[(2,3-Dihydro-1,4-benzodioxin)-5-yl]piperazine
Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-
1-(2,3-DIHYDRO-1,4-BENZODIOXIN-5-YL)-PIPERAZINE HYDROCHLORIDE
1-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-5-YL)PIPERAZINE HYDROCHLORIDE
[Molecular Formula]

C12H16N2O2
[MDL Number]

MFCD06245586
[MOL File]

98224-03-4.mol
[Molecular Weight]

220.27
Chemical PropertiesBack Directory
[storage temp. ]

Store at RT
[solubility ]

DMSO : ≥ 25 mg/mL (113.50 mM)
[form ]

Powder
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Eltoprazine is a partial agonist at SR-1 and SR-2C. Also, it is a 5-HT1A/1B receptor agonist.
[Biological Activity]

5-HT 1 and 5-HT 2C receptor partial agonist (K i values are 40, 52 and 81 nM for 5-HT 1A , 5-HT 1B and 5-HT 2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo .
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