| Identification | Back Directory | [Name]
PD 117519 | [CAS]
96392-15-3 | [Synonyms]
CI 947
PD 11751
PD 117519
PD 117519,R
N-[(R)-Indan-1-yl]adenosine
N-[(1R)-Indan-1-yl]adenosine
(R)-N-(2,3-Dihydro-1H-indenyl)adenosine
PD-117519;PD 117519;PD117519;CI 947;CI947
N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine
N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine
Adenosine, N-[(1R)-2,3-dihydro-1H-inden-1-yl]- | [Molecular Formula]
C19H21N5O4 | [MDL Number]
MFCD00876438 | [MOL File]
96392-15-3.mol | [Molecular Weight]
383.4 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2mg/mL; DMSO: 5mg/mL; Ethanol: 0.1mg/mL | [form ]
A solid | [color ]
White to off-white | [InChIKey]
FSKMJUWPFLDDRS-BYMDKACISA-N | [SMILES]
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N[C@H]3C4=C(C=CC=C4)CC3)N=C2)[C@H](O)[C@@H]1O |
| Hazard Information | Back Directory | [Uses]
N6-Substituted adenosine receptor agonist; a potential antihypertensive agent. | [in vitro]
PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing. | [storage]
Store at -20°C |
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