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ChemicalBook--->CAS DataBase List--->955900-27-3

955900-27-3

955900-27-3 Structure

955900-27-3 Structure
IdentificationBack Directory
[Name]

1-[(E)-[4-methoxy-3-[(4-nitropyrazol-1-yl)methyl]phenyl]methylideneamino]-3-prop-2-enylthiourea
[CAS]

955900-27-3
[Synonyms]

RK9123016
RK-9123016
RK 9123016
1-[(E)-[4-methoxy-3-[(4-nitropyrazol-1-yl)methyl]phenyl]methylideneamino]-3-prop-2-enylthiourea
Hydrazinecarbothioamide, 2-[[4-methoxy-3-[(4-nitro-1H-pyrazol-1-yl)methyl]phenyl]methylene]-N-2-propen-1-yl-
[Molecular Formula]

C16H18N6O3S
[MOL File]

955900-27-3.mol
[Molecular Weight]

374.42
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

RK-9123016 is a small molecule inhibitor of SIRT2. The compound increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression.
Spectrum DetailBack Directory
[Spectrum Detail]

1-[(E)-[4-methoxy-3-[(4-nitropyrazol-1-yl)methyl]phenyl]methylideneamino]-3-prop-2-enylthiourea(955900-27-3)1HNMR
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