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ChemicalBook--->CAS DataBase List--->943902-10-1

943902-10-1

943902-10-1 Structure

943902-10-1 Structure
IdentificationBack Directory
[Name]

PAQ
[CAS]

943902-10-1
[Synonyms]

PAQ
[Molecular Formula]

C14H11N3
[MOL File]

943902-10-1.mol
[Molecular Weight]

221.26
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 2 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson’s disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson’s disease induced by MPTP.
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