| Identification | Back Directory | [Name]
T5601640 | [CAS]
924473-59-6 | [Synonyms]
T5601640
T56-LIMKi
T-5601640(T56-LIMKi)
T56-LIMKi - T5601640
T5601640;T 5601640;T56-LIMKI
3-methyl-N-[3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]-1,2-oxazole-5-carboxamide
3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
5-Isoxazolecarboxamide, 3-methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C19H14F3N3O3 | [MDL Number]
MFCD08495674 | [MOL File]
924473-59-6.mol | [Molecular Weight]
389.33 |
| Chemical Properties | Back Directory | [Boiling point ]
403.4±45.0 °C(Predicted) | [density ]
1.426±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMF: 30 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 20 mg/ml | [form ]
powder | [pka]
11.41±0.70(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
T 5601640 is a LIMK inhibitor and is used for the treatment of proliferative disorders such as cancer, neurofibromatosis and neuronal differentiation associated disaeses. | [Biochem/physiol Actions]
T56-LIMKi is a LIMK2 inhibitor that reduces phosphorylated cofilin, and induces disassembly of actin stress fibers in NF1-/- MEFs cells. | [storage]
Store at -20°C |
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| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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