| Identification | Back Directory | [Name]
Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- | [CAS]
920289-29-8 | [Synonyms]
AGG-523
Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- | [Molecular Formula]
C28H29FN2O4 | [MOL File]
920289-29-8.mol | [Molecular Weight]
476.54 |
| Hazard Information | Back Directory | [Uses]
AGG-523 (PF-5212371) is a reversible, non-hydroxamate, zinc-binding selective aggrecanase 1 (ADAMTS4) and aggrecanase 2 (ADAMTS5) inhibitor. AGG-523 can be used for the study of osteoarthritis (OA)[1]. | [References]
[1] Wang K, et al. Investigational drugs for the treatment of osteoarthritis. Expert Opin Investig Drugs. 2015;24(12):1539-56. DOI:10.1517/13543784.2015.1091880 |
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